Risk factors

If you have any of these risk factors, see if SANCUSO can help. Then print out the questions and discuss with your healthcare professional.

Personal characteristics that increase your risk of CINV3,4

Acute CINV

Delayed CINV

Younger age

Female

Poor control of symptoms in prior cycles

History of motion sickness

History of nausea with pregnancy

Anxiety

Depression

Absence of alcoholism

Expectation of CINV

Female

Poor control of acute CINV symptoms

Expectation of CINV

History of severe nausea with pregnancy

Certain chemotherapy regimens are more likely to cause CINV2

Greater than 90% chance of developing CINV

30% to 90% chance of developing CINV

AC (doxorubicin or epirubicin with cyclophosphamide)

Carmustine >250 mg/m2

Cisplatin ≥50 mg/m2

Cyclophosphamide >1500 mg/m2

Dacarbazine

Mechlorethamine

Streptozocin

Aldesleukin >12-15 million IU/m2

Amifostine >300 mg/m2

Arsenic trioxide

Azacitidine

Bendamustine

Busulfan >4 mg/d

Carboplatin

Carmustine ≤250 mg/m2

Cisplatin <50 mg/m2

Clofarabine

Cyclophosphamide ≤1500 mg/m2

Cytarabine >200 mg/m2

Dactinomycin

Daunorubicin

Doxorubicin

Epirubicin

Idarubicin

Ifosfamide

Interferon alfa >10 million IU/m2

Irinotecan

Melphalan >50 mg/m2

Methotrexate 250-1000 mg/m2

Oxaliplatin >75 mg/m2

Temozolomide